ESPCI web site

FR
|
EN

ESPCI Paris - PSL
ESPCI Paris - PSL is a major institution of higher education (a French "Grande École d’ingénieurs"), an internationally renowned research center, and a fertile ground of innovation for industry. Founded by the City of Paris in 1882, for over a century the School has attracted leading scientific innovators like Nobel Prize laureates Pierre and Marie Curie, Paul Langevin, Frédéric Joliot-Curie, Pierre-Gilles de Gennes, and Georges Charpak, who continue to contribute to the institution’s international reputation. The School’s culture of excellence remains as vibrant as ever. Fully 60% of (…)
Educational programs
Welcome to PSL University! By joining ESPCI paris- PSL, you also join PSL university and its 17 000 students. You get access to an exceptionnel education in sciences, arts, litterature and culture. From Bachelor to PhD, academic programs cover all the fields from sciences, human and social sciences, engineering and arts. PSL targets high-potential students, from every horizon, an accompagnies them towards excellence. Your education will be operated by ESPCI paris - PSL, and your degree delivered by PSL University. Discover the education programs of PSL University Ingénieur ESPCI Paris (…)
Research
ESPCI Paris - PSL is home to 10 research laboratories (all of them being endorsed and jointly sponsored by CNRS) operating at the frontiers of scientific knowledge and experimental know-how, extending from fundamental research to innovation, and covering areas ranging from polymers to telecommunications, from nanobiophysics to organic synthesis, from environmental science to biomedical imaging, from neurobiology to microfluidics, from soft matter to quantum physics, and from colloids to prototyping for industry. ESPCI researchers publish around 500 scientific articles in leading (…)
Innovation
- Inventions
- Entrepreneurship and business start-ups
ESPCI: generating innovation and jobs ESPCI is also known for its capacity to encourage major innovations. Did you know that as well as radium, polonium, actinium and lutecium, many other objects from our everyday lives were first discovered or created at ESPCI, like the neon tube, the black box, the quartz watch, sonar, wireless technology, self-healing rubber or even ultrafast ultrasound imaging? An entrepreneurial culture More and more graduates create their own companies after graduation or after their PhD. This capacity to innovation is highly valued today. ESPCI courses (…)
Internationalisation
The Department of International Relations is pursuing the intellectual globalisation, ambitioned since the foundation of our institution, in postgraduate education and interdisciplinary research, and welcoming the most talented people from around the world. We are focusing on branding of the iconic French elite engineering education and boosting european and international mobilities throughout the world-distinguished institutions. French Engeering Degree webpage Master Programme webpage Doctoral Study webpage
Support Us
ESPCI Paris is at the center of a large network of partnering agreements. These are three-way institutional partnerships - notably with the City of Paris, and ParisTech -, as well as academic, scientific and industrial partnerships enriched by the School’s energy, expertise and creativity. The commitment to transdisciplinarity extends beyond the School’s Paris campus. Today’s complex scientific and technological issues often demand a broader view and collaboration, with the deployment of complementary, hybrid approaches and the sharing of best practices in order to pool resources and (…)

Doctoral thesis viva voce: Thu-Mai Nguyen

Print version of this article

Contact :

6 December 2012 9:00 » 13:00 — Langevin lecture theater

High-resolution elastography for the assessment of the elastic properties of the cornea and the skin

Thu-Mai Nguyen, doctorante - PhD student Crédits : ESPCI ParisTech
Thu-Mai Nguyen, doctorante - PhD student Crédits : ESPCI ParisTechThis thesis presents the implementation of a quantitative elastography technique for the assessment of the biomechanical properties of thin layered media such as the cornea or the skin. For this purpose, the SSI (Supersonic Shear wave Imaging) method has been upgraded to high ultrasonic frequencies (up to 20 MHz). This method consists in retrieving the stiffness of a medium from the speed of a shear wave propagating through this medium.

In thin-layered organs, the shear wave undergoes a guided propagation which leads to dispersive effects. Thus, we have developed a model to recover quantitatively the shear modulus form the dispersion curves.

We have then obtained maps of the elastic properties of porcine corneas (in both ex vivo and in vivo conditions) and of human dermis in vivo.

Finally, we have demonstrated the feasibility of using SSI for the in vivo monitoring of the corneal stiffening induced by an ophthalmic treatment named "corneal collagen cross-linking". We have also conducted two clinical trials on the human dermis to investigate the elasticity changes induced by skin aging or cutaneous lesions.

After her PhD, Thu-Mai Nguyen is recruited by the University of Washington (Seattle) who proposed a postdoctoral

ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS

10 Rue Vauquelin, 75005 Paris

ESPCI Paris

Educational programs

Research & innovation

Laboratories

Corporate

Become our partner